Two doses of Covid-19 vaccine provide 87% efficacy

The study was carried out by a team including researchers from Nagasaki University.

Taking two doses of vaccine, both from Pfizer and Moderna, is 86,8% effective against developing Covid-19, announced on Tuesday (5) a team including researchers from the University of Nagasaki.

The team's vaccine efficacy data is about 10 percentage points below the numbers presented by the National Institute of Infectious Diseases (NIID).

The researchers, however, conducted the study about a month later, at a point when they believed the alpha variant of the virus had been replaced by the highly transmissible delta.

The team conducted the study in July and August at 10 medical institutions in 9 provinces and examined 890 individuals between 16 and 64 years of age suspected of having been infected with the coronavirus.

Of the 528 people who had not been vaccinated, 213 tested positive. Of the 108 who had received the first dose, 31 tested positive, while only 9 of 159 individuals who had been inoculated twice had been infected with Covid-19.

Results from a study conducted by the NIID from June to July showed that receiving two doses of vaccine was 95% effective.

However, Haruka Maeda, a researcher especially aimed at respiratory infection at Nagasaki University, said the vaccine's effectiveness may have weakened because the delta variant increased in June.

Maeda also emphasized that "despite this, it has been confirmed that the effectiveness of vaccines is still high in Japan as well."

Source: Mainichi


Japanese companies will offer benefits using vaccination app

Companies will collaborate to provide benefits to customers who use a new app showing proof of Covid-19 vaccination.

Japanese companies will collaborate to offer special benefits to customers who use a new smartphone app showing proof of Covid-19 vaccination when they go to restaurants and hotels, the software providers said on Wednesday (6).

About 10 companies have joined the initiative, which aims to attract customers by promoting their measures to prevent coronavirus infections while encouraging people to get vaccinated.

The smartphone app will display proof of vaccination with the user's face on the screen once they record the necessary information after being fully inoculated against Covid-19, according to the app's providers, the Medical Check Propulsion Mechanism and the based medical enterprise. in Tokyo ICheck Co.

The “Wakupass” can be downloaded to smartphones for free and is expected to be released after approval from Apple and others, they said.

Companies that have joined the program include the HIS travel agency, the APA Group, which runs a hotel chain, the sushi restaurant chain Kappa Create, and the J-League Kashima Antlers football team.

Companies are currently preparing special benefits for customers, with Kappa Create planning to offer a 10% discount on food and beverages.

Those who have not been vaccinated and do not submit the app will receive the same service as before.

Source: Mainichi

Saturday: 12 thousand tested positive and record also in 10 provinces

Shizuoka, Gunma, Tochigi and Kanagawa are among the 10 with the worst result of this epidemic of the new coronavirus. See the others.

Until 18:31 on Saturday (12.325) Japan had the worst positive test result for the new coronavirus of this epidemic, 926.037, for the fourth consecutive day, during the Olympic Games. Thus, the cumulative rose to XNUMX infected people.

Ten provinces also had a historical record, starting with Tokyo, with 4.058. The others were 1.580 in Kanagawa, 1.036 in Saitama, 792 in Chiba, 439 in Okinawa, 199 in Kyoto, 170 in Tochigi, 168 in Shizuoka, 136 in Gunma and 58 in Niigata.

The provinces with the highest rate per 100 inhabitants are Okinawa, with 130,17 and Tokyo, with 125,33, respectively. They have 3 times more than the country's average of 41,20.

Other provinces with high numbers on Saturday are Fukuoka with 502, Osaka with 1.040, Hokkaido with 243 and Aichi with an upward trend with 286 tested positive.

The number of critically ill patients has been increasing in the last 10 days. From Friday to Saturday, 41 more, therefore, with a total of 667. The total number of patients on Covid-19 treatment is 77.436 nationwide.

In contrast, 833.422 people recovered.

Sources: News Digest, Ryukyu Shimpo and FNN

Is it possible and safe to combine different vaccines? Some countries in the world already apply doses from two manufacturers

This week, pregnant and postpartum women in Rio de Janeiro who took the first dose of the Astrazeneca vaccine against Covid-19 were authorized by the state government to receive the second dose of a different immunizing agent, from Pfizer. It is a measure contrary to the one recommended by the Ministry of Health.

Then, the states of Rio and Ceará adopted the same measure.

The decision was taken by the municipality of Rio and endorsed by a committee of researchers, without the support of the Ministry of Health, which recommends that pregnant and postpartum women take the first dose of Astrazenca and wait up to 45 days after delivery to complete the vaccination schedule.

Now, those women who received the first dose of Astrazeneca, more than 12 weeks ago, will be able to mix the vaccines and take the second dose of Pfizer.

The decision brought up another discussion: is it possible and safe to combine different vaccines?

In Spain, a survey - not yet reviewed by other scientists - showed good results. Volunteers who took the first dose of Astrazeneca and, two weeks later, the second dose of Pfizer, had a significant increase in the production of antibodies that, in the laboratory, managed to inactivate the coronavirus.

In the UK, Oxford researchers who mixed the doses came to a similar conclusion. But they warned that trials have already shown an increased risk of side effects in this mixed immunization regimen.

None of the studies, neither Spanish nor English, involved pregnant women.

In the Philippines, another trial may be of interest to Brazil, as it combines CoronaVac with six other vaccines: Pfizer, Moderna, Janssen, Astrazeneca and Sputnik. But, is this enough for the national immunization plan to be changed, and allow combination?

Fast thousands around the world are getting mixed vaccines, as in Canada, Portugal and South Korea.

In Germany, Chancellor Angela Merkel took the first dose of Astrazeneca and the second of Moderna, another vaccine produced with MRNA technology, just like Pfizer.

In the United States, where 70% received the first dose and 46% are fully immunized, there is already a study to find out if it is advantageous to give a third booster dose with a different vaccine.

CPI will vote breach of confidentiality of deputies Ricardo Barros and Luis Miranda

BRASILIA — Covid's CPI in the Senate will vote this Tuesday on the breach of confidentiality of government leader Ricardo Barros (PP-PR). The federal deputy was cited by President Jair Bolsonaro as responsible for an alleged corruption scheme in the acquisition of the Indian vaccine Covaxin, according to deputy Luis Miranda (DEM-DF). On Tuesday, senators will also decide whether Miranda will have her secrecy broken.

Miranda said in testimony to the CPI that, when denouncing a possible scheme in the Ministry of Health to President Jair Bolsonaro in March this year, he heard from the president that Ricardo Barros was behind the possible illegal activities.

The commission's agenda for next Tuesday also includes the testimony of civil servant Regina Célia Silva Olivesira, who was appointed by Barros for her position in Health. Barros' request for breach of confidentiality was made by senator Alessandro Vieira (Citizenship- IF).

The senators want to advance the corruption charges involving the federal government's purchase of vaccines that have been made public in recent weeks.

Initially, federal deputy Luis Miranda, and his brother, the Ministry of Health, Luis Roberto Miranda, stated in testimony that they had denounced an alleged corruption scheme in the purchase of the Indian vaccine Covaxin.

Later, a salesman who introduced himself as a representative of the company Davati Medical Supply, from the United States, Luiz Paulo Dominguetti Pereira, stated that he received a bribe from the then director of the Logistics department at the Ministry of Health, Roberto Dias.

As well as the secrecy of Deputy Ricardo Barros, the senators of the commission will vote to break the secrecy of Luis Miranda and Dominguetti. Another Davati representative, Cristiano Alberto Hossri Carvalho, may also be called to testify.

Japan intends to issue a vaccine passport in July

The country should start issuing the document, in coordination with local governments, in July.

According to the Secretary General of the Cabinet, Katsunobu Kato, the government intends to start issuing proof of vaccination against the new coronavirus, called a vaccine passport.

“We are going to enact the Regulations for the Enforcement of the Vaccination Law in mid-July and, after testing the revamped Vaccination Registration System (VRS), in relation to local governments, we would like to start issuing the vouchers. It is scheduled for the end of July”, declared Kato.

At this point, the vaccination passport will be on paper, but later it will be considered to be scanned.

Sources: JNN and Sankei

Government admits made serious mistakes in 70 vaccinations

According to a document compiled by the Government Office on Tuesday (29), 70 cases of "errors that can cause serious health problems" were reported in vaccination, and another 69 cases of "errors with a low risk of causing serious health problems immediately ”. The data are from vaccinations made until the 16th of June.

The most common mistake was “application of the second dose of vaccine at inappropriate intervals”, totaling 33 cases. “Vaccinations with needles used on other people”, “people who received 3 times instead of 2” and “people who received both doses on the same day” were also found.

"We need to think about ways to end these mistakes as vaccination opportunities are gradually increasing," Cabinet Secretary Katsunobu Kato told a news conference.

Kato also commented on the British research that found that the combination of the application of 2 different vaccines is more efficient than the double application of one of the same type. “We were not able to confirm the efficiency and safety of the data from this research, so we do not recommend this type of vaccination”, he said.

Source: ANN

Ministry of Health dismisses director amid allegations of corruption in vaccine purchase

BRASÍLIA – Accused of pressuring public servants to speed up the import of the Indian vaccine Covaxin, even with signs of irregularities in the contract, the director of the Ministry of Health's Logistics Department, Roberto Ferreira Dias, was dismissed from his post. The decision was taken on the morning of Tuesday, 29, according to a note released at night by the Ministry. The text also confirms that the director's resignation will be published in the Official Gazette edition of this Wednesday, 30th.

Ferreira's dismissal comes four days after the testimony to Covid's CPI by deputy Luis Miranda (DEM-DF) and his brother, Luis Ricardo Fernandes Miranda, head of import at the Ministry of Health's Logistics Department. a corruption scheme involving the purchase of Covaxin and cited Ferreira Dias.

The director was nominated for the position by the government leader in the Chamber, Ricardo Barros (Progressistas-PR), former Minister of Health, and by former deputy Abelardo Lupion (DEM-PR). Barros denies having sponsored the director, who assumed the role in the administration of then-minister Luiz Henrique Mandetta.

Last year, Ferreira almost occupied a board of directors at the National Health Surveillance Agency (Anvisa). President Jair Bolsonaro himself withdrew from the nomination, however, after Estadão showed that the director had signed a R$ 133,2 million contract with the Ministry of Health, with evidence of irregularity, to purchase 10 million kits of materials used in covid-19 tests.

Another accusation against him, this time of charging bribes, came from Luiz Paulo Dominguetti Pereira, who introduces himself as a representative of Davatti Medical Supply. On Friday, Covid's CPI will hear the testimony of Dominguetti, who told the Folha de S. Paulo newspaper that he had received from Ferreira Dias a request for a US$ 1 bribe for each dose of the AstraZeneca vaccine purchased by the Bolsonaro government. AstraZeneca denies, however, that Davatti represents it – the American company has already been disallowed by AstraZeneca in Canada.

Senators Randolfe Rodrigues (Rede-AP), vice president of the CPI, and Alessandro Vieira (Cidadania-SE) prepared a request to summon Dominguetti. When they testified to Covid's CPI, deputy Luis Miranda and his brother said they met with Bolsonaro on March 20, at Palácio da Alvorada, and reported the corruption scheme in the Ministry of Health to purchase vaccines.

Reports published in the Minas Gerais press indicate that Davatti may be defrauding the process of purchasing vaccines in the state. The company would have negotiated with city halls, with the objective of obtaining a letter of intent showing interest in the acquisition of immunizers from AstraZeneca. After getting the letter, however, conversations got stuck.

In the case of Covaxin, the Bolsonaro government closed the purchase contract for a price 1.000% higher than that announced by the manufacturer itself, as revealed by Estadão. The Ministry of Health decided to suspend the contract temporarily, this Tuesday, 29, on the recommendation of the Federal Comptroller General (CGU). 

In August 2020, a confidential telegram from the Brazilian embassy in New Delhi informed the government that the Covaxin vaccine, produced by Bharat Biotech, had an estimated price of 100 rupees (US$1,34 a dose). Four months later, in December, another diplomatic communiqué said that the Indian-made product "would cost less than a bottle of water." In February this year, however, the Ministry of Health signed a contract with a price of US$ 15 per unit (R$ 80,70, at the price at the time), the most expensive of the six vaccines purchased so far.

Source: Jornal Estadão SP.

Government will dismiss Health's logistics director, accused of charging bribes on vaccine

The Jair Bolsonaro government will dismiss the director of the Ministry of Health's Logistics Department, Roberto Dias. According to an article in the Folha de S. Paulo newspaper, the vaccine representative said that Dias would have charged a bribe to close a contract for the purchase of the doses.

The Ministry of Health sent to Planalto Palace, on the night of Tuesday, 29, Dias' resignation. Sponsored by Ricardo Barros (PP-PR), government leader in the Chamber, the director has been in office since January 2019, still under Luiz Henrique Mandetta.

According to a statement from the Ministry of Health, the dismissal of Dias will be published in the Official Gazette of the Union on Wednesday, 30. The reason for the dismissal was not informed.

According to the newspaper, Luiz Paulo Dominguetti Pereira, representative of the company Davati Medical Supply, Dias would have charged a bribe of US$ 1 per dose sold, at a dinner in a restaurant in Brasília. The director would not have responded to the newspaper's contacts. Covid's CPI president, Omar Aziz (PSD-AM), said the case will be investigated by the commission.

The logistics department is responsible, at the ministry, for signing contracts. The sector was “allotted” to the PP, Bolsonaro's grassroots party.

Last week, Dias was quoted by the server Luis Ricardo Miranda, in testimony to Covid's CPI, as having made “atypical pressure” for the release of Covaxin. On the same day, his brother, deputy Luis Claudio Miranda (DEM-DF), said that the two took the complaint to Bolsonaro, who would have said it was "Ricardo Barros's roll".

Source: Jornal Estadão SP.

Government plans to start vaccinations for people under 64 in June

Ministry will send vaccination tickets for people under 65 in the month of June.

The Ministry of Health, Work and Welfare (MHLW) has asked local governments to issue vaccination tickets for people under 64 years of age.

According to the ministry, there will be no priority in sending the tickets as it will be difficult for the authorities to know who has a chronic disease at the time of sending them.

The ministry comments that vaccinations could start even earlier than expected if vaccinations for the elderly end.

Tokyo's Sumida neighborhood plans to ship tickets to 175.000 people between the ages of 16 and 64 on 1 June.

The reservation of vaccination will be made primarily for adults between 60 and 64 years, people with chronic diseases and employees of care institutions for the elderly.

“We have vaccines for all citizens. We asked everyone to confirm the time of vaccination”, comments the ministry.

Source: Yomiuri

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